Cellular Biomechanics Laboratory

The Cellular Biomechanics Laboratory works to understand how cancer spreads throughout the body and the mechanisms that tumor cells use to move in and out of the vasculature. The lab studies ways in which a tumor microenvironment affects immune cells function and immunoediting within the microcirculation, especially the role that leukocytes and endothelial cells play in tumor cells extravasation during metastasis.

Current Studies Include:

  • Mechanisms of Melanoma Tumor Cell Extravasation
  • Computational Fluid Dynamics (CFD) Modeling of Leukocyte Facilitated Tumor Cell Adhesion in a Shear Flow
  • Matrix Metalloproteinase Studies
  • Tumor Cell Induced Endothelial Cell Junction Disassembly
  • Cell Deformation and Adhesion Studies
  • Lipid Mediated Signaling in Tumor Cell Activation
  • Cell Motility and Locomotion Studies

Contact Information

Bioengineering Facilities and Labs Bioengineering and biomedical engineering research areas
 
 

About

The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

205 Hallowell Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614