• BE, Biomedical Engineering, Zhejiang University, 2000
• Ph D, Biomedical Engineering, University of Minnesota, 2005

Journal Articles

Qingqing Zhang, Samuel R Cramer, Kevin L Turner, Thomas Neuberger, Patrick J Drew and Nanyin Zhang, 2023, "High-frequency neuronal signal better explains multi-phase BOLD response", NeuroImage, 268, pp. 119887

Joanes Grandjean and Nanyin Zhang, 2023, "A consensus protocol for functional connectivity analysis in the rat brain", Nature Neuroscience, 26, pp. 673–681

Qiong Li and Nanyin Zhang, 2023, "Sex differences in resting-state functional networks in awake rats", Brain Structure and Function, 228, (6), pp. 1411-1423

Kyle W Gheres, Hayreddin S Ünsal, Xu Han, Qingguang Zhang, Kevin L Turner, Nanyin Zhang and Patrick J Drew, 2023, "Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice", Communications Biology, 6, (1), pp. 738

Helen M Kamens, Sam Cramer, Rachel N Hanley, Spencer Chase, Anna Wickenheisser, William J Horton and Nanyin Zhang, 2023, "Neuroimaging of opioid exposure: a review of preclinical animal models to inform addiction research", Psychopharmacology, 240, (12), pp. 2459-2482

Xu Han, Samuel R Cramer and Nanyin Zhang, 2022, "Deriving causal relationships in resting-state functional connectivity using SSFO-based optogenetic fMRI", Journal of neural engineering, 19, (6), pp. 066002

Jiayue Cao, Xiaokai Wang, Jiande Chen, Nanyin Zhang and Zhongming Liu, 2022, "The vagus nerve mediates the stomach-brain coherence in rats", NeuroImage, 263, pp. 119628

Wenyu Tu and Nanyin Zhang, 2022, "Neural underpinning of a respiration-associated resting-state fMRI network", eLife, 11, pp. e81555

Beloate N Lauren and Nanyin Zhang, 2022, "Connecting the dots between cell populations, whole-brain activity, and behavior", Neurophotonics, 9, (3), pp. 032208-032208

Zilu Ma, Qingqing Zhang, Wenyu Tu and Nanyin Zhang, 2022, "Gaining insight into the neural basis of resting-state fMRI signal", NeuroImage, pp. 118960

Qingqing Zhang, Samuel R Cramer, Zilu Ma, K L Turner, K W Gheres, Y Liu, P J Drew and Nanyin Zhang, 2022, "Brain-wide ongoing activity is responsible for significant cross-trial BOLD variability", Cerebral Cortex

Y Gu, L E Sainburg, S Kuang, F Han, J W Williams, Y Liu, Nanyin Zhang, X Zhang, D A Leopold and Liu, 2021, "Brain activity fluctuations propagate as waves traversing the cortical hierarchy", Cerebral Cortex, 31, (9), pp. 3986-4005

Wenyu Tu, Zilu Ma and Nanyin Zhang, 2021, "Brain network reorganization after targeted attack at a hub region", NeuroImage, pp. 118219

S Chumachenko, M Rosal, J Allison, S Person, D Ziedonis, B Nephew, C Moore, Nanyin Zhang, J King and C Fulwiler, 2021, "Keeping weight off: Mindfulness-Based Stress Reduction alters amygdala functional connectivity during weight loss maintenance in a randomized control trial", PLoS One, 16, (1), pp. e0244847

Wenyu Tu, Zilu Ma, Nanyin Ma, David Dopfel and Nanyin Zhang, 2021, "Suppressing anterior cingulate cortex modulates default mode network and behavior in awake rats", Cerebral Cortex, 31, (1), pp. 312-323

Zilu Ma, Wenyu Tu and Nanyin Zhang, 2021, "Increased wiring cost during development is driven by long-range cortical, but not subcortical connections", NeuroImage, 225, pp. 117463

Alexander Verbitsky, David Dopfel and Nanyin Zhang, 2020, "Rodent models of post-traumatic stress disorder: behavioral assessment", Translational Psychiatry, 10, (1), pp. 132

Wei Wei, Yamin Zhang, Yinfei Li, Yajin Meng, Mingli Li, Qiang Wang, Wei Deng, Xiaohong Ma, Lena Palaniyappan, Nanyin Zhang and Tao Li, 2020, "Depth-dependent abnormal cortical myelination in first-episode treatment-naïve schizophrenia", Human Brain Mapping, 41, (10), pp. 2782-2793

C Zhang, P Ni, Y Liu, Y Tian, J Wei, B Xiang, L Zhao, X Li, X Ma, W Deng, W Guo, R Ni, Y Zhang, Q Wang, H Huang, Nanyin Zhang and T Li, 2020, "GABAergic abnormalities associated with sensorimotor cortical-striatal community structure deficits in ErbB4 knockout mice and first-episode treatment-naïve patients with schizophrenia", Neuroscience Bulletin, 36, (2), pp. 97-109

Y Ma, Z Ma, Z Liang, N Thomas and Nanyin Zhang, 2020, "Global brain signal in awake rats", Brain Structure and Function, 225, (1), pp. 227-240

Y Liu, Y Tao, H Ünsal and Nanyin Zhang, 2020, "Automatic Brain Extraction for Rodent MRI Images", Neuroinformatics, 18, pp. 395–406

Yin Lin, Mingli Li, Yi Zhou, Wei Deng, Xiaohong Ma, Qing Wang, Wanjun Guo, Yinfei Li, Lijun Jiang, Xun Hu, Nanyin Zhang and Tao Li, 2019, "Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Nai¨ve Patients with Schizophrenia", Neuroscience Bulletin, 35, (4), pp. 688-696

J B Smith, G DR Watson, Z Liang, Y Liu, Nanyin Zhang and K Alloway, 2019, "A role for the claustrum in salience processing?", Frontiers in Neuroanatomy, 13, (64)

Y Liu and Nanyin Zhang, 2019, "Propagation of spontaneous brain activity in awake rats", Neuroimage, 202, pp. 116176

Xiao Liu, Nanyin Zhang, Catie Chang and Jeff Duyn, 2018, "Co-activation patterns in resting-state fMRI signals", NeuroImage, 180, pp. 485-494

Pablo Perez, Zhiwei Ma, Christina Hamilton, C Sánchez, A Mork, A Pehrson, C Bundgaard and Nanyin Zhang, 2018, "Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat", Neuropharmacology, 128, pp. 379-387

Zhiwei Ma, Pablo Perez, Zilu Ma, Yikang Liu, Christina Hamilton, Zhifeng Liang and Nanyin Zhang, 2018, "Functional atlas of the awake rat brain: a neuroimaging study of rat brain specialization and integration", NeuroImage, 170, pp. 95-112

Y Ma, C Hamilton and Nanyin Zhang, 2017, "Dynamic Connectivity Patterns in Conscious and Unconscious Brain", Brain Connectivity, 7, (1), pp. 1-12

Yurong Gao, Yuncong Ma, Qingguang Zhang, Aaron T Winder, Zhifeng Liang, Lilith Antinori, Patrick Drew and Nanyin Zhang, 2017, "Time to wake up: Studying neurovascular coupling and brain-wide circuit function in un-anesthetized animals", NeuroImage, 153, pp. 382-398

J Smith, Z Liang, G Watson, Kevin D Alloway and Nanyin Zhang, 2017, "Interhemispheric resting-state functional connectivity of the claustrum in the awake and anesthetized states", Brain Structure and Function, 222, (5), pp. 2041-2058

W Lei, W Deng, M Li, Z He, Y Han, C Huang, X Ma, Q Wang, W Guo, Y Li, L Jiang, Q Gong, X Hu, Nanyin Zhang and T Li, 2015, "Gray Matter Volume Alterations in First-episode Drug-naïve Patients with Deficit and Nondeficit Schizophrenia", 234, (2), pp. 219-226

D G Crenshaw, K Asin, W K Gottschalk, Z Liang, Nanyin Zhang and A D Roses, 2015, "Effects of low doses of pioglitazone on resting-state functional connectivity in conscious rat brain", PloS one, 10, (2), pp. e0117973

Z Liang, X Liu and Nanyin Zhang, 2015, "Dynamic resting state functional connectivity in awake and anesthetized rodents", NeuroImage, 104, pp. 89-99

Z Liang, J King and Nanyin Zhang, 2014, "Neuroplasticity to a single-episode traumatic stress revealed by resting-state fMRI in awake rats", NeuroImage, 103, pp. 485-91

W Huang, J A King, W W Ursprung, S Zheng, Nanyin Zhang, D N Kennedy, D Ziedonis and J R DiFranza, 2014, "The development and expression of physical nicotine dependence corresponds to structural and functional alterations in the anterior cingulate-precuneus pathway.", Brain and behavior, 4, (3), pp. 408-17

A D Roses, A M Saunders, M W Lutz, Nanyin Zhang, A R Hariri, K E Asin, D G Crenshaw, K Budur, D K Burns and S K Brannan, 2014, "New applications of disease genetics and pharmacogenetics to drug development", Current opinion in pharmacology, 14, pp. 81-9

Z Liang, T Li, J King and Nanyin Zhang, 2013, "Mapping thalamocortical networks in rat brain using resting-state functional connectivity", NeuroImage, 83, pp. 237-44

W Huang, J R DiFranza, D N Kennedy, Nanyin Zhang, D Ziedonis, S Ursprung and J A King, 2013, "Progressive levels of physical dependence to tobacco coincide with changes in the anterior cingulum bundle microstructure", PLoS one, 8, (7), pp. e67837

M E Heffernan, W Huang, K M Sicard, B T Bratane, E M Sikoglu, Nanyin Zhang, M Fisher and J A King, 2013, "Multi-modal approach for investigating brain and behavior changes in an animal model of traumatic brain injury", Journal of Neurotrauma, 30, (11), pp. 1007-12

Z He, W Deng, M Li, Z Chen, L Jiang, Q Wang, C Huang, D A Collier, Q Gong, X Ma, Nanyin Zhang and T Li, 2013, "Aberrant intrinsic brain activity and cognitive deficit in first-episode treatment-naive patients with schizophrenia.", Psychological medicine, 43, (4), pp. 769-80

S Qi, Y Mu, K Liu, J Zhang, Y Huan, Q Tan, M Shi, Q Wang, Y Chen, H Wang, H Wang, Nanyin Zhang, X Zhang, L Xiong and H Yin, 2013, "Cortical inhibition deficits in recent onset PTSD after a single prolonged trauma exposure.", NeuroImage: Clinical, 3, pp. 226-33

Z Liang, J King and Nanyin Zhang, 2012, "Intrinsic organization of the anesthetized brain", The Journal of neuroscience : the official journal of the Society for Neuroscience, 32, (30), pp. 10183-91

C E Fulwiler, J A King and Nanyin Zhang, 2012, "Amygdala-orbitofrontal resting-state functional connectivity is associated with trait anger.", Neuroreport, 23, (10), pp. 606-10

Z Liang, J King and Nanyin Zhang, 2012, "Anticorrelated resting-state functional connectivity in awake rat brain", NeuroImage, 59, (2), pp. 1190-9

Z Liang, J King and Nanyin Zhang, 2011, "Uncovering intrinsic connectional architecture of functional networks in awake rat brain.", The Journal of neuroscience : the official journal of the Society for Neuroscience, 31, (10), pp. 3776-83

W Huang, M E Heffernan, Z Li, Nanyin Zhang, D H Overstreet and J A King, 2011, "Fear induced neuronal alterations in a genetic model of depression: an fMRI study on awake animals", Neuroscience letters, 489, (2), pp. 74-8

Nanyin Zhang, X H Zhu, E Yacoub, K Ugurbil and W Chen, 2010, "Functional MRI mapping neuronal inhibition and excitation at columnar level in human visual cortex", Experimental brain research, 204, (4), pp. 515-24

Nanyin Zhang, P Rane, W Huang, Z Liang, D Kennedy, J A Frazier and J King, 2010, "Mapping resting-state brain networks in conscious animals", Journal of neuroscience methods, 189, (2), pp. 186-96

Nanyin Zhang, X H Zhu, Y Zhang, J K Park and W Chen, 2010, "High-resolution fMRI mapping of ocular dominance layers in cat lateral geniculate nucleus.", NeuroImage, 50, (4), pp. 1456-63

Z Liu, C Rios, Nanyin Zhang, L Yang, W Chen and B He, 2010, "Linear and nonlinear relationships between visual stimuli, EEG and BOLD fMRI signals", NeuroImage, 50, (3), pp. 1054-66

Nanyin Zhang, E Yacoub, X H Zhu, K Ugurbil and W Chen, 2009, "Linearity of blood-oxygenation-level dependent signal at microvasculature.", NeuroImage, 48, (2), pp. 313-8

L Ding, Nanyin Zhang, W Chen and B He, 2009, "Three-dimensional imaging of complex neural activation in humans from EEG", IEEE transactions on bio-medical engineering, 56, (8), pp. 1980-8

Z Liu, Nanyin Zhang, W Chen and B He, 2009, "Mapping the bilateral visual integration by EEG and fMRI", NeuroImage, 46, (4), pp. 989-97

X Bai, Z Liu, Nanyin Zhang, W Chen and B He, 2009, "Three-dimensional source imaging from simultaneously recorded ERP and BOLD-fMRI", IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 17, (2), pp. 101-6

X H Zhu, Nanyin Zhang, Y Zhang, K Ugurbil and W Chen, 2009, "New insights into central roles of cerebral oxygen metabolism in the resting and stimulus-evoked brain", Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 29, (1), pp. 10-8

X H Zhu, F Du, Nanyin Zhang, Y Zhang, H Lei, X Zhang, H Qiao, K Ugurbil and W Chen, 2009, "Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by Mitochondria.", Methods in molecular biology (Clifton, N.J.), 489, pp. 317-57

X Zhu, F Du, Nanyin Zhang, H Lei, K Ugurbil and W Chen, 2009, "New opportunities for high-field in vivo MRS in studying brain bioenergetics and function", Brain Imaging and Behavior, 2, (4), pp. 232-241

Nanyin Zhang, X H Zhu and W Chen, 2008, "Investigating the source of BOLD nonlinearity in human visual cortex in response to paired visual stimuli", NeuroImage, 43, (2), pp. 204-12

Nanyin Zhang, X H Zhu, Y Zhang and W Chen, 2008, "An fMRI study of neural interaction in large-scale cortico-thalamic visual network.", NeuroImage, 42, (3), pp. 1110-7

F Du, X H Zhu, Y Zhang, M Friedman, Nanyin Zhang, K Ugurbil and W Chen, 2008, "Tightly coupled brain activity and cerebral ATP metabolic rate", Proceedings of the National Academy of Sciences of the United States of America, 105, (17), pp. 6409-14

Nanyin Zhang, Z Liu, B He and W Chen, 2008, "Noninvasive study of neurovascular coupling during graded neuronal suppression", Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 28, (2), pp. 280-90

X H Zhu, Y Zhang, Nanyin Zhang, K Ugurbil and W Chen, 2007, "Noninvasive and three-dimensional imaging of CMRO(2) in rats at 9.4 T: reproducibility test and normothermia/hypothermia comparison study", Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 27, (6), pp. 1225-34

C H Im, A Gururajan, Nanyin Zhang, W Chen and B He, 2007, "Spatial resolution of EEG cortical source imaging revealed by localization of retinotopic organization in human primary visual cortex", Journal of neuroscience methods, 161, (1), pp. 142-54

C H Im, Z Liu, Nanyin Zhang, W Chen and B He, 2006, "Functional cortical source imaging from simultaneously recorded ERP and fMRI", Journal of neuroscience methods, 157, (1), pp. 118-23

Nanyin Zhang and W Chen, 2006, "A dynamic fMRI study of illusory double-flash effect on human visual cortex.", Experimental brain research, 172, (1), pp. 57-66

Nanyin Zhang, X H Zhu and W Chen, 2005, "Influence of gradient acoustic noise on fMRI response in the human visual cortex.", Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 54, (2), pp. 258-63

X H Zhu, Nanyin Zhang, Y Zhang, X Zhang, K Ugurbil and W Chen, 2005, "In vivo 17O NMR approaches for brain study at high field", NMR in biomedicine, 18, (2), pp. 83-103

Nanyin Zhang, X H Zhu, H Lei, K Ugurbil and W Chen, 2004, "Simplified methods for calculating cerebral metabolic rate of oxygen based on 17O magnetic resonance spectroscopic imaging measurement during a short 17O2 inhalation", Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 24, (8), pp. 840-8

X H Zhu, Y Zhang, R X Tian, H Lei, Nanyin Zhang, X Zhang, H Merkle, K Ugurbil and W Chen, 2002, "Development of (17)O NMR approach for fast imaging of cerebral metabolic rate of oxygen in rat brain at high field.", Proceedings of the National Academy of Sciences of the United States of America, 99, (20), pp. 13194-9

M Li, W Deng, Z He, Q Wang, C Huang, L Jiang, Q Gong, D Ziedonis, J King, X Ma, Nanyin Zhang and Tao Li, , "A splitting mind: imbalanced internal and external worlds in schizophrenia", 232, pp. 145-153

Z Liang, G Watson, Kevin D Alloway, Thomas Neuberger, G Lee and Nanyin Zhang, , "Mapping the functional network of medial prefrontal cortex in awake rodents using optogenetic fMRI", NeuroImage, 117, pp. 114-123

A Lee, D Gansler, Nanyin Zhang, M Jerram, J King and C Fulwiler, , "Relationship of mindful awareness to neural processing of anger stimuli and impact of mindfulness training", Psychiatry Research: Neuroimaging, 264, pp. 22-28

D Dopfel, P Perez, A Verbitsky, H Bravo-Rivera, Y Ma, G J Quirk and Nanyin Zhang, , "Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD", Nature Communications, 10, (1), pp. 1-12

C Hamilton, Y Ma and Nanyin Zhang, , "Global Reduction of Information Exchange during Anesthetic-Induced Unconsciousness", Brain Structure and Function, 222, pp. 3205–3216

Y Fu, Z Ma, C Hamilton, Z Liang, X Hou, X Ma, X Hu, H Meng, Q He, W Deng, Y Wang, L Zhao, T Li and Nanyin Zhang, , "Genetic influences of resting-state neural networks: a twin study", Human Brain Mapping, 36, pp. 3959–3972

Zilu Ma, Yuncong Ma and Nanyin Zhang, , "Development of brain-wide connectivity architecture in awake rats", Neuroimage, 176, pp. 380-389

Yikang Liu, Pablo Perez, Zilu Ma, Zhiwei Ma, David Dopfel, Samuel Cramer, Wenyu Tu and Nanyin Zhang, , "An open database of resting-state fMRI in awake rats", NeuroImage, 220, pp. 1170942

Nanyin Zhang, , "Anomalous gray matter structural networks in recent onset post-traumatic stress disorder", Brain imaging and behavior, 12, (2), pp. 390-401

Zhiwei Ma and Nanyin Zhang, , "Temporal transitions of spontaneous brain activity", eLife, 7, pp. e33562

Zhiwei Ma and Nanyin Zhang, , "Cross-population Myelination Covariance of Human. Human Brain Mapping", Human Brain Mappping, 38, (9), pp. 4730-4743

Zhifeng Liang, Yuncong Ma, Glenn Watson and Nanyin Zhang, , "Simultaneous GCaMP6-based Fiber Photometry and fMRI in Rats", Journal of Neuroscience Methods, 289, pp. 31-38

David Dopfel and Nanyin Zhang, , "Mapping stress networks using functional magnetic resonance imaging in awake animals", Neurobiology of Stress, 9, pp. 251-263

W Lei, B Kirkpatrick, Q Wang, W Deng, M Li, W Guo, S Liang, Y Li, C Zhang, X Li, P Zhang, Z Li, B Xiang, J Chen, X Hu, Nanyin Zhang and T Li, , "Progressive brain structural changes after the first year of treatment in first-episode treatment-naive patients with deficit or nondeficit schizophrenia", Psychiatry Research: Neuroimaging, 288, pp. 12-20

Conference Proceedings

W Chen, X Liu, X H Zhu and Nanyin Zhang, 2009, "Functional MRI study of brain function under resting and activated states.", Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2009, pp. 4061-3

Nanyin Zhang, X H Zhu, Z Liu, B He and W Chen, 2008, "Quantitatively Interpreting fMRI signal.", Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2008, pp. 4415-8

Nanyin Zhang, X H Zhu and W Chen, 2006, "Probing fast neuronal interaction using fMRI.", Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 1, pp. 13-6

• September 2017 - June 2023, "A multimodal approach to understanding the development of neurovascular coupling," (Sponsor: National Institute of Neurological Disorders and Stroke).

• July 2017 - July 2021, "Mechanistic dissection of the neural basis of the resting-state fMRI signal using multi-modal approaches," (Sponsor: National Institute of Mental Health).

• June 2018 - January 2019, "Evaluating Therapeutic Effects of Selective Serotonin Reuptake Inhibitors (SSRIs) in Animal Model of Stress-Related Disorders Using Behavioral and Imaging Methods," (Sponsor: Alkermes, Inc.).

• Fellow of International Academy of Medical and Biological Engineers (IAMBE), International Academy of Medical and Biological Engineers (IAMBE), 2023

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