Journal Articles

Wennan Zhao, Danish Ahmad, Jennifer Toth, Rebecca Bascom and William E Higgins, 2023, "Endobronchial Ultrasound Image Simulation for Image-Guided Bronchoscopy", IEEE Transactions on Biomedical Engineering, 70, (1), pp. 318-330

Xiaonan Zang, Wennan Zhao, Jennifer Toth, Rebecca Bascom and William E Higgins, 2022, "Multimodal Registration for Image-Guided EBUS Bronchoscopy", Journal of Imaging, 8, (7), pp. 1-18

Trevor K Kuhlengel, William E Higgins and Rebecca Bascom, 2022, "Efficient Procedure Planning for Comprehensive Lymph Node Staging Bronchoscopy", Journal of Medical Imaging, 9, (5), pp. 055001-1 --- 055001-22

William E Higgins, Trevor Kuhlengel, Danesh Ahmad, Daniel Guck, M. Chopra, D. Shore, J. Nuschke and Rebecca Bascom, 2022, "Image-Guided Bronchoscopy for Comprehensive Lymph Node Staging: A Phantom Study", American J. Respiratory and Critical Care Medicine, 205, pp. A3666-A3667

Xiaonan Zang, Ronnarit D Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Catherine Abendroth, Thomas Allen, Rickhesvar Mahraj, Jennifer Toth, Rebecca Bascom and William E Higgins, 2021, "Image-Guided EBUS Bronchoscopy System for Lung-Cancer Staging", Informatics in Medicine Unlocked, 25, (100665), pp. 13

William E Higgins, Trevor Kuhlengel and Rebecca Bascom, 2021, "Automatic Procedure Planning for Comprehensive Bronchoscopic Lymph Node Staging", Americian J. Respiratory and Critical Care Medicine, 203, (May), pp. 2 pages

William E Higgins, Wennan Zhao, Danish Ahmad, Jennifer Toth and Rebecca Bascom, 2021, "Multimodal Virtual Bronchoscopic Guidance of Radial-Probe EBUS for Peripheral Nodule Biopsy: A Phantom Study", Americian J. Respiratory and Critical Care Medicine, 203, (May), pp. 1 page

William E Higgins, Trevor Kuhlengel and Rebecca Bascom, 2020, "Automated 3D-CT-based Lymph Node Station Definition for the IASLC 8th edition Guidelines", Americian J. Respiratory and Critical Care Medicine, 201, (May), pp. A4447-A4448

Xiaonan Zang, Jason D Gibbs, Ronnarit Cheirsilp, Patrick Byrnes, Jennifer Toth, Rebecca Bascom and William E Higgins, 2019, "Optimal Route Planning for Image-Guided EBUS Bronchoscopy", Computers in Biology and Medicine, 112, pp. 103361

William E Higgins, Patrick Byrnes, Wennan Zhao, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Virtual Reality Viewing of the Airway Mucosa: Bronchoscopic Video Analysis Fused with CT Images", Americian J. Respiratory and Critical Care Medicine, 199, pp. A2617-A2618

William E Higgins, Xiaonan Zang, Patrick Byrnes, Ronnarit Cheirsilp, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Route Planning for Predicting the Feasibility and Yield of Bronchoscopic Biopsy during Central-Chest Lymph Node Staging", American J. Respiratory and Critical Care Medicine, 199, pp. A2346-A2347

Patrick Byrnes and William E Higgins, 2019, "Efficient Bronchoscopic Video Summarization", IEEE Transactions on Biomedical Engineering, 66, (3), pp. 848-863

William E Higgins, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2017, "Optimal Biopsy-Site Localization for Image-Guided Endobronchial Ultrasound", American J. Respiratory and Critical Care Medicine, 195

Xiaonan Zang, Rebecca Bascom, Christopher Gilbert, Jennifer Toth and William E Higgins, 2016, "Methods for 2D and 3D Endobronchial Ultrasound Image Segmentation", IEEE Trans. Biomedical Engineering, 63, (7), pp. 1426-1439

William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2016, "System for Multimodal Image-Guided Endobronchial Ultrasound: Human Pilot Study", Americian J. Respiratory and Critical Care Medicine, 193, pp. A4382-83

William E Higgins, Ronnarit Cheirsilp, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth, Thomas Allen and Rebecca Bascom, 2016, "PET/CT Image Registration for Multimodal Bronchoscopic Procedure Planning and Guidance", Americian J. Respiratory and Critical Care Medicine, 193, pp. A4381

Rahul Khare, Rebecca Bascom and William E Higgins, 2015, "Hands-Free System for Bronchoscopy Planning and Guidance", IEEE Trans. Biomedical Engineering, 62, (12), pp. 18

Ronnarit Cheirsilp, Rebecca Bascom, Thomas W. Allen and William E Higgins, 2015, "Thoracic Cavity Definition for 3D PET/CT Analysis and Visualization", Computers in Biology and Medicine, 62, (7), pp. 15

William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Anne Dimmock, Thomas Allen, Christopher Gilbert, Rickhesvar Mahraj, Jennifer Toth and Rebecca Bascom, 2015, "Multimodal Image-Guided System for Bronchoscopy: Human Feasibility Study", Americian J. Respiratory and Critical Care Medicine, 191

William E Higgins, Ronnarit Cheirsilp, Trevor Kuhlengel, Thomas Allen, Rickhesvar Mahraj and Rebecca Bascom, 2015, "Computer-based 3D PET/CT Thoracic ROI Detection, Definition, and Visualization", Americian J. Respiratory and Critical Care Medicine, 191

William E Higgins, X. Zang, P. D. Byrnes, R. Cheirsilp, T. Kuhlengel, A. E. Dimmock, J. W. Toth, C. Gilbert and R. Bascom, 2014, "Multimodal Image-Guided Intervention System for Bronchoscopy and EBUS Fusion", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1

William E Higgins, R. Khare, D. C. Cornish, X. Zang, R. Cheirsilp, P. D. Byrnes, J. W. Toth, M. Reed and R. Bascom, 2014, "Technician-Free Image-Guided Bronchoscopy System: A Human Study", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1

William E Higgins, D. C. Higgins, D. C. Cornish, R. Khare, J. Toth, M. Reed and R. Bascom, 2014, "Sensor-based Bronchoscopy Guidance System: Human Studies", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1

Jason D. Gibbs, Michael W. Graham, Rebecca Bascom, Duane C. Cornish, Rahul Khare and William E Higgins, 2014, "Optimal procedure planning and guidance system for peripheral bronchoscopy", IEEE Trans. Biomedical Engineering, 61, (3), pp. 20

Scott M. Merritt, Rahul Khare, Rebecca Bascom and William E Higgins, 2013, "Real-time CT-Video registration for the continuous guidance of bronchoscopy", IEEE Transactions on Medical Imaging, 32, (8), pp. 1376-1396

Other

Xioanan Zang, Mikhail Breslav and William E Higgins, 2013, "3D Segmentation and Reconstruction of Endobronchial Ultrasound", 8675

Ronnarit Cheirsilp and William E Higgins, 2013, "Multimodal 3D PET/CT System for Bronchoscopic Procedure Planning", 8670

Rahul Kare, Rebecca Bascom and William E Higgins, 2013, "Technician-free system for image-guided bronchoscopy", 8671

• Inventor of the Year, Invent Penn State, October 2019

• Senior Member, National Academy of Inventors, February 2019

• Life Fellow, IEEE, January 2023

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