• BS, Chemical Engineering, University of Oklahoma, 2003
• Ph D, Biomedical Engineering, University of Virginia, 2008

Books

Justin Lee Brown, Sangamesh G Kumbar and Brittany L Banik, 2016, Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine, Academic Press, Amsterdam, Netherlands, pp. 239

Sarfaraz K Niazi and Justin Lee Brown, 2015, Fundamentals of Modern Bioprocessing, Taylor and Francis, Boca Raton, FL, USA

Journal Articles

Pouria Fattahi, Yin-Ting Yeh, Tiankai Zhao, Mousa Younesi, Changjin Huang, Mauricio Terrones Maldonado, Siyang Zheng, Justin Lee Brown, Dan D Huh, Sulin Zhang and Peter J Butler, 2023, "Endothelial cell selectivity to nanoparticles depends on mechanical phenotype", Advanced Materials Interfaces, 10, (18)

Daniel T Bowers, MaryElizabeth McCulloch and Justin Lee Brown, 2023, "Evaluation of Focal Adhesion Mediated Subcellular Curvature Sensing in Response to Engineered Extracellular Matrix", Biointerphases, 18, (2)

Daniel T Bowers and Justin Lee Brown, 2022, "Nanofiber curvature with Rho GTPase activity increases mouse embryonic fibroblast migration velocity", Integrative Biology, 13, (12), pp. 295-308

Tugba Ozdemir, Erdal Senocak, Gene Gerber, Secil Erden Tayhan and Justin Lee Brown, 2022, "The Pull of Tissue Engineering: A STEM Outreach Program with a Modular Cyclic Stretch Device to Engage High Scholl", Biomedical Engineering Education, 2, (1), pp. 9

Brittany L Banik and Justin Lee Brown, 2020, "3D-Printed Bioreactor Enhances Potential for Tendon Tissue Engineering", Regenerative Engineering and Translational Medicine

Emily G Long, Merve Buluk, Michelle B Gallagher, Jennifer M Schneider and Justin Lee Brown, 2019, "Human Mesenchymal Stem Cell Morphology, Migration, and Differentiation on Micro and Nano-textured Titanium", Bioactive Materials, 4, pp. 249-255

Daniel T Bowers and Justin Lee Brown, 2019, "Nanofibers as Bioinstructive Scaffolds Capable of Modulating Differentiation Through Mechanosensitive Pathways for Regenerative Engineering", Regenerative Engineering and Translational Medicine, 5, pp. 22-29

Tugba Ozdemir, Daniel T Bowers, Xiang Zhan, Debashis Ghosh and Justin Lee Brown, 2019, "Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening", Scientific Reports, 9, (1001), pp. 1-13

Greg Risser, Brittany L Banik, Justin Lee Brown and Jeffrey M Catchmark, 2017, "Structural Properties of Starch-Chitosan-Gelatin Foams and the Impact of MC3T3 Mouse Osteoblast Cell Viability", Journal of Biological Engineering, 11, (1), pp. 9

P Fattahi, J T Dover and Justin Lee Brown, 2017, "3D Near-Field Electrospinning of Biomaterial Microfibers with Potential for Blended Microfiber-Cell-Loaded Gel Composite Structures", Advanced Healthcare Materials, 6, (19), pp. 9

Brittany L Banik, Thomas R Riley, Christina J Platt and Justin Lee Brown, 2016, "Human Mesenchymal Stem Cell Morphology and Migration on Micgrotextured Titanium", Frontiers in Bioengineering and Biotechnology, 4, (41), pp. 9

Brittany L Banik, Pouria Fattahi and Justin Lee Brown, 2016, "Polymeric Nanoparticles: The Future of Nanomedicine", WIREs Nanomedicine & Nanobiotechnology, 8, (2), pp. 271-299

B L Banik, Gregory Stephen Lewis and Justin Lee Brown, 2016, "Multiscale Poly(e-caprolactone) Scaffold Mimicking Non-linearity in Tendon Tissue Mechanics", Regenerative Engineering and Translational Medicine, 2, (1), pp. 1-9

D Jaiswal, R James, N B Shelke, M D Harmon, Justin Lee Brown, F Hussain and S G Kumbar, 2015, "Gelatin Nanofiber Matrices derived from Schiff Base Derivative for Tissue Engineering Applications", Journal of Biomedical Nanotechnology, 11, (11), pp. 2067-2080

Changjun Huang, Tugba Ozdemir, Lichong Xu, Peter J Butler, Christopher A Siedlecki, Justin Lee Brown and Sulin Zhang, 2015, "The role of substrate topography on the cellular uptake of nanoparticles.", Journal of Biomedical Materials Research Part B, 104B, (3), pp. 488-495

A M Higgins, B L Banik and Justin Lee Brown, 2015, "Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter.", Integrative Biology, 7, (2), pp. 229-36

R T Tran, L Wang, M Huan, W Tang, Z Zhang, D Jin, B L Banik, Justin Lee Brown, Z Xie and X Bai, 2014, "Synthesis and characterization of biomimetic citrate-based biodegradable composites", 102A, (8), pp. 2521-2532

A M Higgins, B L Banik and Justin Lee Brown, 2013, "Nanotopography sensing through intracellular signaling and mechanotransduction with an emphasis on bone", 3, (4), pp. 396-408

T Ozdemir, A M Higgins and Justin Lee Brown, 2013, "Osteoinductive biomaterial geometries for bone regenerative engineering.", Current pharmaceutical design, 19, (19), pp. 3446-3455

T Ozdemir, L Xu, C Siedlecki and Justin Lee Brown, 2013, "Substrate curvature sensing through MyosinIIA upregulates early osteogenesis", Integrative Biology, 5, (11), pp. 1407-1416

D Jaiswal and Justin Lee Brown, 2012, "Nanofiber diameter-dependent MAPK activity in osteoblasts", Journal of Biomedical Materials Research Part A, 100, (11), pp. 2921-8

Justin Lee Brown, M S Peach, L S Nair, S G Kumbar and C T Laurencin, 2010, "Composite scaffolds: bridging nanofiber and microsphere architectures to improve bioactivity of mechanically competent constructs", Journal of Biomedical Materials Research Part A, 95A, (4), pp. 1150-1158

M Deng, L S Nair, S P Nukavarapu, S G Kumbar, Justin Lee Brown, N R Krogman, Harry R Allcock and C T Laurencin, 2010, "Biomimetic, Bioactive Etheric Polyphosphazene-Poly(lactide-co-glycolide) Blends for Bone Tissue Engineering", Journal of Biomedical Materials Research Part A, 92, (1), pp. 114-125

M S Peach, S G Kumbar, Justin Lee Brown and C T Laurencin, 2009, "Recent Developments in Nanoparticle Based Targeted Delivery of Chemotherapeutics", Current Bioactive Compounds, 5, (3), pp. 170-84

Justin Lee Brown, L S Nair and C T Laurencin, 2008, "Solvent/Non-Solvent Sintering: A Novel route to Create Porous Microsphere Scaffolds for Tissue Regeneration", Journal of Biomedical Materials Research Part B, 86, (2), pp. 396-406

S P Nukavarapu, S G Kumbar, Justin Lee Brown, N R Krogman, L S Nair, Harry R Allcock and C T Laurencin, 2008, "Polyphosphazene/Nano-Hydroxyapatite Composite Microsphere Scaffolds for Bone Tissue Engineering", Biomacromolecules, 9, (7), pp. 1818-25

Justin Lee Brown, L S Nair, J Bender, Harry R Allcock and C T Laurencin, 2007, "The Formation of an Apatite Coating on Carboxylated Polyphosphazenes via a Biomimetic Process", Materials Letters, 61, (17), pp. 3692-95

Herbert H Lipowsky, Daniel T Bowers, Brittany L Banik and Justin Lee Brown, , "Mesenchymal Stem Cell Deformability and Implications for Microvascular Sequestration", Annals of Biomedical Engineering, pp. 15

Conference Proceedings

Elizabeth R Byers, Michelle B Gallagher, James Sugar and Justin Lee Brown, 2023, "Characterization of the mechanical state of human mesenchymal stem cells on micro- or nano-textured Ti6Al4V surfaces", Canadian Journal of Surgery, 66, pp. S50

Vraj Shah, Michelle B Gallagher, Aaron Cheung and Justin Lee Brown, 2022, "Spatial and depth mapping of nascent mineralization on Ti6Al4V surfaces demonstrating hierarchical macro- micro- nanoscale surface features", Canadian Journal of Surgery, 65, pp. S130-S131

Merve Buluk, Jess Frith and Justin Lee Brown, 2019, "Controlling Stem Cell Fate via Highly Organized 2.5 Dimensional Bio-Instructive Fibrous Scaffolds", Proceedings of the 2019 Biomedical Engineering Society Annual Fall Meeting

Justin Lee Brown, Jennifer M Schneider and Michelle B Gallagher, 2019, "Human Mesenchymal Stem Cell Morphology, Migration, and Differentiation on Micro- and Nano-Textured Titanium", ORS 2019 Annual Meeting ePosters

Brittany L Banik, Jennifer M Schneider, Michelle B Gallagher and Justin Lee Brown, 2019, "In Vitro Response to Implants with Internally Roughened Micron and Nano Features", ORS 2019 Annual Meeting ePosters

Pouria Fattahi, Jordan T Dover and Justin Lee Brown, 2016, "3D Near-Field Electrospinning: A New Approach for 3D Fiber:Cell-loaded Gel Composites", Proceedings of the 2016 Biomedical Engineering Society Annual Fall Meeting

Pouria Fattahi, Y T Yeh, Siyang Zheng, Sulin Zhang, Justin Lee Brown and Peter J Butler, 2016, "Optimal Nanoparticle Uptake by Cells is Dictated by Morphology", Proceedings of the 2016 Biomedical Engineering Society Annual Fall Meeting

Daniel T Bowers, Mary Elizabeth McCulloch and Justin Lee Brown, 2016, "Focal Adhesion Activation State Drives Cell Migration Velocity Dependence on Matrix Mimetic Nanofiber Diameter", Proceedings of the 2016 Biomedical Engineering Society Annual Fall Meeting

Brittany L Banik and Justin Lee Brown, 2016, "Exploring Synergy Between Mechanical and Bioinstructive Cues for the Tendon:Bone Interface", Proceedings of the 2016 Biomedical Engineering Society Annual Fall Meeting

Brittany L Banik and Justin Lee Brown, 2016, "Understanding the Cell Niche for Tendon Tissue Engineering through Physical Scaffold Cues", Proceedings of the 10th World Biomaterials Congress

Pouria Fattahi, Jordan T Dover and Justin Lee Brown, 2016, "Automated and Highly Controllable 3D Near-Field Electrospinning of Polymeric Microfibers with Potential for Tissue Engineering Applications", Proceedings of the 10th World Biomaterials Congress

Daniel T Bowers and Justin Lee Brown, 2016, "Focal Adhesion Composition During Attachment to Electrospun Nanofibers of Varying Diameters", Proceedings of the 10th World Biomaterials Congress

R Wolfe and Justin Lee Brown, 2015, "The Effects of Fiber Density on Adherens Junctions and Localization of Beta-Catenin", Proceedings of the 2015 Biomedical Engineering Society Annual Fall Meeting

B L Banik and Justin Lee Brown, 2015, "Understanding Substrate Mediated Signaling Mechanisms to Augment Tendon Regeneration", Proceedings of the 2015 Biomedical Engineering Society Annual Fall Meeting

D T Bowers and Justin Lee Brown, 2015, "Integrins Involved in Sensing and Adhering to Electrospun Nanofibers", Proceedings of the 2015 Biomedical Engineering Society Annual Fall Meeting

P Fattahi, Sulin Zhang, Peter J Butler and Justin Lee Brown, 2015, "The Role of Cell Mechanics and Morphology in Nanoparticle Uptake", Proceedings of the 2015 Biomedical Engineering Society Annual Fall Meeting

B L Banik and Justin Lee Brown, 2015, "Innovative Tendon Scaffold Design Based on a Bioinstructive, Biomimetic, and Multiscale Approach", Proceedings of IEEE EMBC

Justin Lee Brown, 2015, "Molecular Mechanisms Orchestrating the Stem Cell Response to Translational Scaffolds", Proceedings of IEEE EMBC

C Huang, P Fattahi, H S Muddana, Justin Lee Brown, Sulin Zhang and Peter J Butler, 2015, "Mecanotargeting of Nanoparticles to Vascular Endothelium", Proceedings of the International Society of Biorheology

B L Banik and Justin Lee Brown, 2015, "Bioinstructive Scaffolds Through a Multiscale Approach Mimicking Tissue Mechanics and Regulating Differentiation", Transactions of the 39th Annual Meeting of the Society for Biomaterials

P Fattahi, Peter J Butler and Justin Lee Brown, 2015, "The Effect of Induced Cell Alignment on the Endocytosis of Nanoparticles", Proceedings of the 2015 Society for Biomaterials Annual Meeting

Justin Lee Brown, 2015, "Bio-Instructive Scaffolds: Guiding Design Through Understanding Intracellular Geometry Sensing", Proceedings of the 2015 Cellular and Molecular Bioengineering Conference

J T Dover and Justin Lee Brown, 2014, "Precise Triaxial Deposition of Near Field Electrospun Nanofibers for the Fabrication of Tissue Scaffolds", Proceedings of the 2014 Biomedical Engineering Society Annual Fall Meeting

R Nagurney and Justin Lee Brown, 2014, "Beta-Catenin Signaling Leading to Cell Maintenance or Differentiation in Response to Electrospun Fibers", Proceedings of the 2014 Biomedical Engineering Society Annual Fall Meeting

B L Banik and Justin Lee Brown, 2014, "POR1 Geometry Sensing of Nanofiber Diameter Regulates Rac1 Activity and Osteoblast Differentiation", Proceedings of the 2014 Biomedical Engineering Society Annual Fall Meeting

Justin Lee Brown, 2014, "Bio-Instructive Scaffolds: Guiding Design Through Understanding Intracellular Geometry Sensing", Proceedings of the 2nd Frontiers in Bioengineering Symposium

T Ozdemir, C Huang, L Xu, Peter J Butler, Christopher A Siedlecki, Sulin Zhang and Justin Lee Brown, 2014, "The Role of Substrate Topography on the Endocytosis of Nanoparticles", Proceedings of the 2014 Society for Biomaterials Annual Meeting

T Ozdemir, X Zhan, D Ghosh and Justin Lee Brown, 2014, "High-throughput siren Screening Reveals Substrate Topography Induced Osteogenecity in Cooperation with Focal Adhesion and Autocrine Growth Factor Signaling Pathways", Proceedings of the 2014 Society for Biomaterials Annual Meeting

B L Banik and Justin Lee Brown, 2013, "Novel Poly(caprolactone) (PCL) Scaffold Architecture for Tendon Tissue Engineering Applications", Proceedings of the 2013 Biomedical Engineering Society Annual Fall Meeting

R T Tran, B L Banik, Justin Lee Brown and Jian Yang, 2013, "Biomimetic Citrate-Presenting Osteoinductive Composites", Transactions of the 37th Annual Meeting of the Society for Biomaterials

T Ozdemir, G Meyers, B Cornell, G Gerber, Margaret J Slattery and Justin Lee Brown, 2013, "Integrating creative thinking into biomaterial education: LEGO Tissue Engineering Kit", Proceedings of the 2013 Society for Biomaterials Annual Meeting

A M Higgins and Justin Lee Brown, 2013, "Vesicle trafficking as a mechanism to sense and respond to nanofiber architecture", Proceedings of the 2013 Society for Biomaterials Annual Meeting

B L Banik and Justin Lee Brown, 2013, "Novel Poly(caprolactone) (PCL) Scaffold Architecture for Tendon Tissue Engineering Applications", Proceedings of the 2013 Society for Biomaterials Annual Meeting

T. Ozdemir and J. L. Brown, 2012, "Efficacy of MAPK singaling in osteoblast progenitor phenotype on electrospun nanofibers.", Proceedings of the 9th World Biomaterials Congress

A. Higgins and J. L. Brown, 2012, "Vesicle trafficking as a mechanism to sense and respond to nanofiber architecture.", Proceedings of the 2012 Biomedical Engineering Society Annual Fall Meeting, pp. 158

D Jaiswal and J L Brown, 2012, "Influence of nanofiber diameter on ERK and p38 activation in osteoblastic cells", Proceedings of the 9th World Biomaterials Congress, pp. 0

T Ozdemir and J L Brown, 2011, "Dynamic regulation of osteoblast growth signals in response to ECM-like electrospun nanofibers", College of Engineering Research Symposium (CERS 2011), pp. 0

T Ozdemir and J L Brown, 2011, "Electrospun polymeric nanofibers for controlling the cellular modulators of MAPK signaling in differentiating osteoblast cells", Proceedings of the 2011 Biomedical Engineering Society Annual Fall Meeting, pp. 0

D Jaiswal and J L Brown, 2011, "Mechanotransduction of osteoblasts on nanofibers: The influence of fiber diameter on zyxin mechanosensing", Proceedings of the 2011 Biomedical Engineering Society Annual Fall Meeting, pp. 0

C Hong and J L Brown, 2011, "Role of Nanofiber architecture in NFkB signaling", Proceedings of the 2011 Biomedical Engineering Society Annual Fall Meeting, pp. 0

T Ozdemir and J L Brown, 2011, "Nanofiber mediated osteoinduction through MAPK signaling", College of Engineering Research Symposium (CERS 2011), pp. 0

Justin Lee Brown, 2008, "Composite Microsphere/Nanofiber Scaffolds for Bone Tissue Engineering", Proceedings of the 8th World Biomaterials Congress

S P Nukavarapu, N R Krogman, S G Kumbar, Justin Lee Brown, L S Nair, Harry R Allcock and C T Laurencin, 2007, "Novel Composite Polyphosphazene Hydroxyapatite Scaffolds for Bone Tissue Engineering", Proceedings of the 2007 Society of Biomaterials Annual Meeting

Justin Lee Brown, L S Nair and C T Laurencin, 2007, "Novel Biodegradable Polyphosphazene Lighter than Water Microsphere Scaffolds for Bioreactor Based Bone Tissue Engineering", The Proceedings of the 2007 Society for Biomaterials Annual Meeting

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